Product name: Celastrol
Synonym : Tripterin; Tripterine; 3-Hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid;
(2R,4aS,6aS,6aR,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
Molecular Formula : C29H38O4
Mol. Weight : 450.61
CAS No. : 34157-83-0
Botanical Source : Chinese Thunder of God vine(leigongteng)
Tripterygium wilfordii Hook. f.
Catalogue No. : C07059
Purity : > 98% by HPLC
Packaging : 10mg, 20mg, 50mg, 100mg, 1g,10g, 100g...
Package and quantity according to customer's detail requirement.
Remark : In stock, customized for large scale.
Celastrol is a potent anti-inflammatory that is extracted from the root bark of an ivy-like vine in China. Celastrol was used for years as a natural remedy for inflammatory conditions. Several pharmaceutical companies are studying its multiple properties and have found it to be quite intensely immunosuppressive as well as anti-inflammatory. Celastrol inhibits macrophage activation, MHC I and II processing, TNF-alpha, IL1, IL2, and IL6.
Reference :
1,Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer’s disease.
Prog Neuropsychopharmacol Biol Psychiatry. 2001 Oct;25(7):1341-57.
2,Celastrol, a Triterpene Extracted from the Chinese 'Thunder of God Vine,' Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice
Cancer Research 66, 4758-4765, May 1, 2006